BOCTOPUS2 predicted the topology of transmembrane β-barrel proteins, using the dyad-repeat pattern of their strands.
The code remains available on GitHub: ElofssonLab/BOCTOPUS2 (program) and ElofssonLab/web_boctopus2 (web server).
Reference: Hayat S, Peters C, Shu N, Tsirigos KD, Elofsson A. Inclusion of dyad-repeat pattern improves topology prediction of transmembrane β-barrel proteins. Bioinformatics 32:1571–1573 (2016). doi:10.1093/bioinformatics/btw025
For α-helical membrane proteins, see TOPCONS.